LeSS and SAFe are both methods for scaling agile software development.
LeSS focuses on identifying the core of your product and removing all non-essential features, while SAFe focuses on identifying the core of your organization and removing all non-essential functions. Both approaches help teams stay focused on their mission by cutting down on distractions and improving communication.
LeSS is an iterative approach to scaling Agile software development. It uses the "whole team" concept, in which all of the people who are working on a project are responsible for its success. This means that everyone from product managers to developers to testers are involved in every stage of the project, including determining what needs to be done and how it should be done. LeSS also focuses on continuous delivery of working software, rather than building big deliverables at the end of each iteration.
SAFe is based on Lean principles and focuses on creating an incremental approach towards scaling Agile software development. SAFe uses a modified version of Scrum and Kanban methods for this purpose. It also emphasizes that teams should work together as cross-functional units instead of siloed departments or roles within an organization structure (which can lead to bottlenecks).